Listed below are links to software tools to help with isotope production R&D. Numerous codes relevant for this work are available at RSICC - Radiation Safety Information Computational Center which distributes codes for nuclear-related research.
Iso-Chain: Almanza, C. L., Lovett, H. A., Schmitrroth, F., Garland, M. A. and Mirzadeh, S.
"Iso-Chain: A UserFriendly, Two-Group Nuclear Transmutation and Decay Code," Proceedings, ANS Mid-Winter 6
Meeting and Technology Expo, Albuquerque, New Mexico, November 12-16, 2006, pp. 441-442
SCALE 6 with ORIGEN-ARP: SCALE 6: Standardized Computer Analyses for Licensing Evaluation Modular Code System for Workstations and Personal Computers, Including ORIGEN-ARP
ORIGEN: ORIGEN-JENDL32: Isotope Generation and Depletion Code with Libraries based on JENDL 3.2. (note: CCC-750/SCALE 6 with ORIGEN-ARP is generally recommended for new ORIGEN users)
MCNP: MCNP5/MCNPX: Monte Carlo N-Particle Transport Code System Including MCNP5 1.60 and MCNPX 2.6.0 and Data Libraries (Source & Executables)
If you have codes you would like to have listed here, please contact email@example.com.