eparation of Ce-134 from dissolved lanthanum target by anion exchange chromatography.
A robust supply of Ce-134 is an essential step in advancing the use of alpha emitters for cancer therapy due to its promise as a PET imaging analog for actinium-225 (Ac-225) and thorium-227 (Th-227).
DOE Seal
The DOE Office of Science is excited to announce it is accepting proposals for the 2023 DOE Office of Science Early Career Research Program to support the research of outstanding scientists early in their careers.
The Department of Energy Isotope Program is pleased to announce cerium-139 (Ce-139) has been added to our catalog and is available for purchase.

DOE Isotope Program Highlights

Left: production rate as a function of proton energy of parent radioisotopes selenium-72 (Se-72) (1) & germanium-68 (Ge-68) (2). Right, a Positron Emission Tomography (PET) image of a patient with metastatic colon cancer, obtained using gallium-68 (Ga-68)

Fighting Cancer on Earth and in Space Using High-Energy Protons

Scientists on Earth use high-energy protons to create isotopes to detect and treat cancer. In space, however, these same high-energy protons can pose a risk to spacecraft and the health of the astronauts traveling in them.
Image courtesy of Texas A&M University The medical radioisotope astatine is separated from bismuth then loaded into a resin column. Once dry, the column is packed for shipping so the astatine can be sent for use at a cancer treatment center.

Cancer Countermeasures on a Column

University researchers produce a novel method of shipping the promising medical isotope astatine-211
Image courtesy of Oak Ridge National Laboratory and Army Research Laboratory. Direct deposition of a radioisotope source onto a converter. This can improve conversion of the radioisotope source’s beta decay emissions to electricity by using two converters instead of one. The result is greater power density for the power source.

New Approach to Radioisotope Power Sources for Improved Efficiency, Long Life

NextGen power sources may satisfy the need for long-term, compact power for use in remote or extreme environments.
Image courtesy of Carlos Jones, Oak Ridge National Laboratory Researcher Sandra Davern looks at non-radioactive metal ions enclosed in biodegradable polymers in her lab at Oak Ridge National Laboratory. Her work is paving the way for enclosing isotopes in the same polymers for targeted treatment of cancer cells.

Enclosing Radiation-Loaded Particles to Better Seek and Destroy Cancer

Promising study details how radioactive agents could be sent directly to cancer cells.