Browse job openings within the U.S. Department of Energy’s Isotope Program, NIDC, national laboratories and university facilities stewarded by the program.


To apply to an open position, click the link and follow the instructions included for that position. You may also send an email to with the position title, location and attached cover letter and resume. Once received, our staff will assist you in applying for the position.

Division Director, Radioisotope Science and Technology Division

The Isotope Science and Engineering Directorate (ISED) of the Oak Ridge National Laboratory (ORNL) seeks applicants for the Division Director of the Radioisotope Science and Technology Division (RSTD). This position reports to the ISED Associate Laboratory Director (ALD). The incumbent will be responsible for leading and managing the science and technology capabilities within the Division consistent with existing programmatic missions and emerging opportunities, and for establishing and implementing strategies for future directions. The RSTD performs radioisotope research and development (R&D) and production. ORNL produces two-thirds of radioisotopes in the DOE portfolio, for use in national security, medicine, industry, research, and deep space exploration.  

Research Technician

We are looking for a Research Technician to be part of the team supporting operations and program maintenance activities in the Hot Cell (HC) Facility as part of the IP. The IP Hot Cell Facility is a laboratory designed to handle high dose rate radiological materials. It has hot cells equipped with telemanipulators to remotely handle high dose rate materials along with general laboratory space with specialized equipment to support isotope processing activities.

The Mechanical Research Technician is responsible for the upkeep and programmatic maintenance of the hot cells and associated facility equipment. The work includes mechanical and electrical work for the maintenance of the analytical and programmatic equipment within the general hot cell facility, maintenance of the hot cell train and telemanipulators, and interface with the facility personnel for building-wide systems. The successful candidate will develop and update technical and safety procedures, and support technical work for isotope production operations. The successful candidate must be able to work with radioactive materials and in radiologically contaminated areas, become respirator fit, and perform work with remote manipulators as part of a high-performing team to meet deliverables for the IP.

Isotope Program Manager

The LANL Isotope Program (IP), an important component of LANL’s Office of Science program portfolio, is seeking outstanding candidates for the position of Program Manager 4 (PM 4). The LANL IP has unique capabilities at the Los Alamos Neutron Science Center (LANSCE) accelerator and robust hot cell capabilities within the Chemistry Division that enable the production, purification, and qualification of radioisotopes for distribution through the DOE Isotope Program. The role of the Program Manager 4 is to provide overall leadership and management for the LANL IP in strategic planning and execution of work at the Isotope Production Facility (IPF) and the Hot Cell Facility to deliver on a diverse set of production, service and research missions for the DOE IP. The program also maintains a glovebox line within the Plutonium Facility for DOE IP. The PM 4 is responsible for communication with the DOE program managers, with the National Isotope Development Center (NIDC, for interface to customers), and with multiple levels of management across LANL where work for the program is executed. The program manager also oversees a robust research portfolio that spans across isotope-related disciplines including high current targetry, nuclear physics, radiochemistry, and exploring new capabilities for future production.

R&D Associate in Radiotherapeutics

The Isotope Applications Group at ORNL is seeking a highly motivated research scientist with experience in the areas of targeted radiotherapy, nanomedicine, or radiobiology. The Isotope Applications Research Group is involved in advancing radioisotope technologies, for medical, industrial, research, and national security applications.

This position will focus on using nanotechnology to encapsulate radioisotopes for conjugation to targeting vectors and evaluating their effectiveness using in vitro cell models. The successful candidate should have a strong background in radiochemistry, inorganic chemistry, organic chemistry, nanotechnology, or radiobiology.

IPF Engineering Technologist

We are looking for an Engineering Technologist to join our Team as an Isotope Production Facility operator, providing electro/mechanical and operational support for the irradiation of production and R&D targets at the Los Alamos Neutron Science Center (LANSCE). The successful candidate will be responsible for supporting both routine and R&D production runs, performing facility maintenance including radiological work, participating in experimental development activities, assisting in the troubleshooting and maintenance of the many complex IPF systems, as well as providing seasonal 24/7 off-hours and on-call support. Production and R&D activities will be performed in a facility that includes a Hot Cell designed to handle high dose rate materials. The ability to function as a member of a coordinated team is critical, as is a commitment to quality research, technical excellence, and professional integrity.

Postdoctoral Research Associate - Separations Chemistry

We are seeking a Postdoctoral Research Associate who will support the Isotope Applications Research Group in the Radioisotope Science and Technology Division (RSTD), Isotope Science and Engineering Directorate (ISED) at Oak Ridge National Laboratory (ORNL) in the area of separations science. Specifically, this role involves high-pressure ion chromatography. 

The Isotope Applications Research Group is involved in advancing radioisotope technologies, for medical, industrial, research, and national security applications. RSTD is a global leader in actinide science, delivering innovations in isotope production technology, enabling ORNL to produce and rapidly deliver radioisotopes for science, medicine, industry, and security.

Established in 2020, the Isotope Science and Engineering Directorate is strengthening Oak Ridge National Laboratory's leadership in isotope production and enrichment technology innovation. ISED is guiding the Lab's pursuit of the fundamental science and technology that broadens the application of isotopes for energy, environmental, medical, and national security purposes. These efforts are made possible through the High Flux Isotope Reactor, the Radiochemical Engineering Development Center, ORNL's other nuclear facilities, and an assemblage of world-leading scientists and engineers.  Please visit for more information about ISED.

Postdoctoral Research Associate - Separations Chemistry

We are seeking a Postdoctoral Research Associate in the area of separations science who will support the Emerging Isotopes Research Group in the Radioisotope Science & Technology Division (RSTD), Isotope Science & Engineering Directorate (ISED) at Oak Ridge National Laboratory (ORNL). In this role you will synthesize and characterize small organic compounds used in the separation of metals followed by testing via liquid-liquid or solid-liquid separation methods.

The Emerging Isotopes Research Group is responsible for the development and evaluation of advanced radioisotope separation techniques to be applied toward efficient and cost-effective radioisotope production. RSTD is a global leader in actinide science, delivering innovations in isotope production technology, enabling ORNL to produce and rapidly deliver radioisotopes for science, medicine, industry, and security.

Postdoctoral Research Associate

The Cyclotron Institute at Texas A&M University has an immediate opening for a Postdoctoral Research Associate position as part of a DOE-sponsored program on radioisotope research and production with accelerator beams. The successful candidate will be invited to participate in an interdisciplinary research project involving the production, purification, and characterization of At-211and the incorporation of At-211 into inorganic and organometallic compounds. Candidates experienced in handling radioactivity are particularly encouraged to apply.  Knowledge in synthetic inorganic and organometallic chemistry is also desirable even if not strictly required.  The candidate should have strong writing and communications skills with the ability to work as part of a team. The successful candidates will also be expected to develop radiolabeling protocols for various compounds and to perform radiochemical separations. This position will involve the handling of radioisotopes that are beta, alpha, gamma, and/or PET emitters and may involve the handling of hazardous chemicals so attention to details is a must.  The molecular aspects of the project will be carried out with input from (or under the joint supervision of) François Gabbaï.  Interested persons should send a CV to Sherry Yennello (

EI&C Engineer-Senior R&D Staff Member

The Testing Science and Cascade Engineering Section within the Enrichment Science and Engineering Division (ESED) is seeking a Research Professional – Senior EI&C Engineer for the Electrical, Instrumentation, and Controls Engineering Group. This group is focused on the development of testbeds and enrichment systems by human-machine interface research and system logic development and this position will have an emphasis in the areas of instrumentation hardware and software to make a significant contribution to projects involving isotope enrichment, nuclear nonproliferation, and instrumentation of mission-critical systems. This group develops and implements advanced control system architectures for centrifuge testbeds.

Isotope Program Operator

The successful candidate will join the Medical Isotope Research and Production Group (MIRP) of the Collider-Accelerator Department. The MIRP group has an opening for a MIRP Operator to aid in the research and process of isotopes at the target processing laboratory in building 801. The operator will be responsible for working in the laboratory performing chemical processing and separations.  Further conducting analytical measurements to assess purity and quantification.  The main program focus is to produce and distribute radioisotopes for nuclear medicine research and clinical practice and to develop radioisotopes for new applications in medicine and science.  The group’s major facilities include the Brookhaven Linac Isotope Producer (BLIP) and a fully-equipped hot laboratory with hot cells, radiochemistry research laboratories, and analytical equipment.  The BLIP utilizes high-intensity proton beams of up to 200 MeV. The MIRP group resides in the Collider-Accelerator Department. This position has a high level of interaction with an international and multicultural scientific community.