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On May 30, 2024, the DOE Isotope Program hosted a Virtual Roundtable on Best Practices and Safe Handling of Radium-226 (Ra-226), featuring invited speakers from the international community. As interest in targeted alpha therapies increases, so does the demand for Ra-226 feedstock to produce key alpha-emitters, including Ac-225, Ac-227/Th-227/Ra-223, Th-228/Ra-224/Pb-212, and Th-229. Radium-226’s physical properties present unique and challenging handling requirements, particularly its decay product radon-222. A panel of national and international speakers provided candid discussions on best practices, types of facilities, appropriate capabilities, and technical challenges to an audience of over 200 participants. Following the presentations, a Question & Answer session was held.
DOE Isotope Program Virtual Roundtable on Best Practices and Safe Handling of Radium-226 Presentations
Ra-226 Roundtable –Opening Remarks
Harvesting of legacy radium sources; experiences and approaches at BWXT Medical
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Radiation protection issues associated to design and operation of facilities using Ra-226 for production of isotopic generators for alpha-radioimmunotherapy
*This presentation is not included in the recording but is available for viewing.
Best Practices in Processing Obsolete Brachytherapy Sources at PNNL
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Current Experiences in Handling Ra-226 at SpectronRx
Handling of Ra-226 feedstock at ORNL
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Historic experience, lessons learned and future strategies in handling large quantities of Ra-226 in hot cell facilities
